A simple method for screening assessment of skin and eye irritation.

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Skin irritation and sensitization: mechanisms and new approaches for risk assessment. 1. Skin irritation.

Cutaneous irritation presents a major health problem with serious social and occupational impact. The interaction between an irritant and the human skin depends on multiple factors: the intrinsic properties and the nature of the irritant itself, and specific individual- and environment-related variables. The main pathological mechanisms of irritancy include skin barrier disruption, induction of...

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ژورنال

عنوان ژورنال: The Journal of Toxicological Sciences

سال: 1994

ISSN: 0388-1350,1880-3989

DOI: 10.2131/jts.19.25